Cupron Cosmetic Trial
Double-Blind, Parallel, Randomized Clinical Trial


Double-Blind, Parallel, Randomized Clinical Trial to Determine the Efficacy in Improving Cosmetic Attributes of Facial Skin when Using Cupron (Copper-Oxide Containing) Pillowcases 

Study Report Please read the copyright notice below IMPORTANT NOTICE:  This report and its contents are © copyright 2008 by Cupron Inc., all rights reserved.  Any quotation or reproduction of this report may occur only after express written permission from Cupron Inc.  Please contact gadi@cupron.com.

 Summary

* Fifty-seven individuals, (55 women and two men), completed a 4 week, double blind, parallel, randomized clinical study.  The participants used either copper-oxide containing pillowcases or pillowcases not containing copper-oxide (the “placebo control pillow cases”).  Photographs were taken by a professional photographer of each participant at three times:  The beginning (baseline) of the Trial, and at 2 and 4 weeks after the commencement of the Trial.

* An expert grader (dermatologist) evaluated the face for the effect on the following cosmetic facial skin attributes of those individuals using both the copper-oxide containing pillowcases and the placebo control pillowcases: wrinkles; crowsfeet/fine lines; blemishes; skin glow; texture; and general appearance.  These qualities were evaluated at the baseline, 2, and 4 weeks.

 

Conclusions

* There was a statistically significant reduction of the appearance of facial wrinkles and crowsfeet/fine lines and statistically significant improvement in the texture and overall appearance of facial skin when consistently sleeping for 4 weeks on 0.4% (weight/weight) copper-oxide containing pillowcases (the Cupron pillowcases) versus the placebo control pillowcases.  In most trial participants, this statistically significant effect was already noticeable within 2 weeks of using the copper-oxide containing pillowcases.

“Before” and “After” photographs were taken of all trial participants.  The following are examples of photos from the statistically significant majority of clinical trial participants in which effects were observed as compared to the control group.


 “Before” and “After” photographs were taken of all trial participants.  The following are examples of photos from the statistically significant majority of clinical trial participants in which effects were observed as compared to the control group.


 

“Before” and “After” photographs were taken of all trial participants.  The following are examples of photos from the statistically significant majority of clinical trial participants in which effects were observed as compared to the control group.


This latest clinical trial conducted in 2008 confirms the results of previous double-blind, parallel, randomized clinical testing conducted by an independent clinical testing laboratory to determine efficacy in improving cosmetic attributes of facial skin when using Cupron (copper-oxide containing) pillowcases.  For more information about the science of Cupron and skin, please visit http://www.cupron.com/Cupron-Reference-Materials/.